The research included 200 subjects, of which 150 had angiographically proven coronary disease with the coronary artery stenosis of 50% or more, and 50 subjects who did not have angiographically proven coronary disease. Patients were chosen randomly out of approximately 1000 patients who underwent angiography. All the subjects were treated at the Clinical Center of University of Tuzla – at the Clinic for Cardiovascular Diseases. The average value of homocysteine concentration in plasma of patients with angiographically proven coronary disease was 13.86 μmol/L, and 10.65 μmol/L in the controls, which is statistically significant difference (P [Med Arch 2009; 63(5.000): 256-260]

oronary artery disease, homocysteine, ejective fraction