Purpose. Vaccination is the fastest, most efficient and the cheapest measure to prevent communicable diseases. The purpose of the work was to evaluate the results of primary vaccination as well as the first revaccination by DPT,OPV and MMR vaccines. Work method. Descriptive epidemiological study was used. The investigation was done in the Primary Health Center in Nis and it involved all the children who were born in 2000, 2001, 2006 and 2007. Work results. A total number of 1863 vaccination records were examened. In the sample of examened records of children who were born in 2000 and 2001, there were 155 children (12.05%) who were vaccinated with different vaccines and according to the different vaccination schedules. The number of childern born in 2006 and 2007 was slightly higher and it was (14.70%). In the first group (children who were born in 2000 and 2001) there were 43 children (4.51%) who were not vaccinated (3 children havent been vaccinated by DPT, and other 40 havent been vaccinated by MMR). Similar situation wass in the second group (children who were born in 2006 and 2007) in which 37 children (4.03%) havent been vaccinated at all (3 of them by DPT and other 34 by MMR). In both observed groups DPT vaccine immunization started out late. 48.25% of children from the first group havent been vaccinated with the first dose of DPT on time. 58.53% of children born in 2006 and 2007 havent been vaccinated with the first dose of DPT on time. The first re-vaccination by DPT was also late in children born 2000 and 2001 (16.6% vs 45.36%). It was also delayed the first revaccination by MMR (10,3% vs 22,53%). Discussion. To achieve the expected effects should be vaccinated at least 95% of planned persons but also make timely vaccinations. While the main goal of immunization is to prevent illness and death, the overriding concern of any public health intervention must be Primum non nocere. Conclusion. A small number of post-vaccinal reactions is registered, and there havent been registered cases of adverse events following immunization or serious reactions that would be contraindications for further immunization. [Med Arch 2010; 64(4.000): 235-239]
immunization, post-vaccinal reactions, surveillance
